KMID : 0376419800040010241
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Chonbuk University Medical Journal 1980 Volume.4 No. 1 p.241 ~ p.242
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Chronic hepatitis and fibrosis due to paracetamol
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Abstract
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Chronic hepatitis and fibrosis developed in a man who had been taking 3.0 gm of paracetamol daily for about a year. Liver biopsy done 30 days after the drug Was stopped showed prominent diffuse central necrosis and portal changes. This prompted anti-inflamatory treatment, with subsequent improvement, in liver pathology. Chronic ingestion of therapeutic doses of paracetamol may produce hepatic necrosis and hepatitis and fibrosis.
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KEYWORD
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